| Deoxyribonucleic Acid (DNA) | Ribonucleic Acid (RNA) |
|---|---|
| It occurs mainly in the nucleus of the cell. | It occurs in the cytoplasm of the cell. |
| It has double stranded α-helix structure in which two strands are coiled spirally in opposite directions. | It has single stranded α -helix structure. |
| The sugar molecule is 2-deoxyribose. | The sugar molecule is ribose. |
| Nitrogenous base uracil is not present. | Nitrogenous base thymine is not present. |
| It has the unique property of replication. | It usually does not replicate. |
| It is responsible for the transmission for heredity character. | It helps in protein biosynthesis. |
| DNA molecules are very large, their molecular masses may vary from 6 X 106 – 16 X 106 u. | RNA molecules are much smaller with molecular mass ranging from 2 X 104 – 4 X 104 u. |
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